产品货号:
Z16481
中文名称:
FGF19抗体
英文名称:
Anti-FGF19 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FGF19 Antibody |
指标别名 | FGF 19;FGF19;fibroblast growth factor 19 |
克隆性 | Polyclonal |
检验物种 | mouse,rat |
应用范围 | IHC |
基因名称 | FGF19 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived rat FGF19 recombinant protein (Position:R26-K218).Rat FGF19 shares 53.2% and 96.4% amino acid (aa) sequence identity with human and mouse FGF19,respectively. |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | FGF19,Fibroblast growth factor 19,is a protein that in humans is encoded by the FGF19 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family.The FGF19 gene is mapped to 11q13.3.The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family.Expression of this gene was detected only in fetal but not adult brain tissue.Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis.The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and,instead,are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity.The orthologous protein in mouse is FGF15,which shares about 50% amino acid identity and has similar functions.Together they are often referred to as FGF15/19. |
Uniprot ID | Q8VI81 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | fibroblast growth factor 19 |
蛋白名全称 | Fibroblast growth factor 15 |
推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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